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Vitamins, carotenoids, polyphenols, melatonin, caffeine, N-acetylcarnosine and N-acetylcysteine are strong antioxidants that target oxidative stress in the pathogenesis of cataracts (19,28,107,118,132,145,176)
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Interestingly, melatonin also scavenges free radicals and supports endogenous detoxification enzymes like superoxide dismutase (SOD), glutathione peroxidase (GPX1), and glutathione reductase (GSR)